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Base‐Promoted Synthesis of β ‐Ketophosphine Oxides from Diphenylphosphorylallenes
Author(s) -
Ruan LiHeng,
Wang Qiang,
Sun Jing,
Zhou MingDong
Publication year - 2018
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201800348
Subject(s) - chemistry , pyrrolidine , base (topology) , transition metal , transformation (genetics) , base metal , combinatorial chemistry , reaction conditions , metal , organic chemistry , catalysis , metallurgy , mathematical analysis , biochemistry , mathematics , gene , materials science , welding
The transition‐metal‐free synthesis of β ‐ketophosphine oxides from diphenylphosphorylallenes in the presence of pyrrolidine and silica gel has been developed under mild reaction conditions. This simple and efficient transformation tolerates a wide range of diphenylphosphorylallenes with different functional groups, and affords the desired products in moderate to excellent yields.