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Palladium/Acid‐Catalyzed Straightforward Allylation of Arenes using 1‐Substituted Propynes via Aryl C−H Bond Activation
Author(s) -
Minami Yasunori,
Furuya Yuki,
Hiyama Tamejiro
Publication year - 2018
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201800234
Subject(s) - chemistry , regioselectivity , palladium , aryl , catalysis , medicinal chemistry , stereochemistry , combinatorial chemistry , organic chemistry , alkyl
The title reaction of heteroarenes or electron‐deficient arenes with 1‐substituted propynes took place via C(sp 2 )−H bond activation in arenes to give the corresponding allylarenes in a straightforward and regioselective manner. When 1,2,4,5‐tetrafluorobenzene was used, a double allylation product, bis(2‐propen‐1‐yl)tetrafluorobenzene, was isolated.
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