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Recent Developments in the C(sp 3 )−H Functionalization of 2‐Oxindoles through Radical Reactions
Author(s) -
Chen WeiTing,
Wei WenTing
Publication year - 2018
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201800209
Subject(s) - chemistry , surface modification , combinatorial chemistry , molecule , organic chemistry , nanotechnology , materials science
3‐Substituted 2‐oxindoles are prevalent in a variety of natural products and bioactive compounds. As such, the synthesis of these molecules is highly desirable. This Focus Review provides a critical overview of recent developments (in particular, reports since 2013) in the C(sp 3 )−H functionalization of 2‐oxindoles through radical reactions. The main achievements in this field are presented according to the bonds that are formed. Special attention is paid to the reaction mechanisms, and a personal outlook on future developments in this research area is provided.
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