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Fickle Reactivity of Allenes in Transition‐Metal‐Catalyzed C−H Functionalizations
Author(s) -
Santhoshkumar Rajagopal,
Cheng ChienHong
Publication year - 2018
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201800133
Subject(s) - chemistry , annulation , catalysis , transition metal , combinatorial chemistry , carbon atom , selectivity , reactivity (psychology) , surface modification , carbon fibers , organic chemistry , ring (chemistry) , materials science , composite number , composite material , medicine , alternative medicine , pathology
Transition‐metal‐catalyzed C−H functionalizations with allenes lead to unique selectivity challenges due to the presence of two adjacent carbon–carbon double bonds, which enables a series of atom‐ and step‐economical alkenylation, allenylation, allylation, dienylation, and annulation reactions of different substrates. This Focus Review highlights the recent remarkable advancements made in transition‐metal‐catalyzed C−H functionalization with allenes.