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Access to Furo[2,3‐ b ]pyridines by Transition‐Metal‐Free Intramolecular Cyclization of C3‐substituted Pyridine N ‐oxides
Author(s) -
Wang Dong,
Shen Meng,
Wang Yuxi,
Hu Jianyong,
Zhao Junjie,
Yu Peng
Publication year - 2018
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201800082
Subject(s) - chemistry , intramolecular force , pyridine , transition metal , scope (computer science) , nucleophile , substrate (aquarium) , nucleophilic substitution , combinatorial chemistry , computational chemistry , stereochemistry , medicinal chemistry , organic chemistry , catalysis , oceanography , computer science , programming language , geology
Two transition‐metal‐free synthetic methods for the construction of furo[2,3‐ b ]pyridines have been developed by intramolecular nucleophilic addition/rearomatization strategy. Remarkable features of the methods include simple operation, wide substrate scope, and easily accessible starting materials.

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