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Catalyst‐Free Regioselective Sulfenylation of Imidazoheterocycles with Sulfonyl Hydrazides in Water
Author(s) -
Chowdhury Soumyadeep Roy,
Fadikar Pulak,
Ul Hoque Injamam,
Maity Soumitra
Publication year - 2018
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201700670
Subject(s) - chemistry , regioselectivity , sulfonyl , thio , catalysis , organic chemistry , combinatorial chemistry , alkyl
A simple, efficient and catalyst‐free sulfenylation of imidazoheterocycles with sulfonyl hydrazides has been developed in water under additive free condition. This method is highly regioselective, and the corresponding thio products were obtained in good to excellent yields. Experimental studies were indicative of the formation of sufonothioate intermediates from sufonyl hydrazides as the active thiol carrier for this transformation.