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Cover Feature: Robust Hydrogenation of Nitrile and Nitro Groups to Primary Amines Using Ni 2 P as a Catalyst and Ammonia Borane under Ambient Conditions (Asian J. Org. Chem. 11/2017)
Author(s) -
Zen YunFeng,
Fu ZiCheng,
Liang Fei,
Xu Yong,
Yang DanDan,
Yang Zhi,
Gan Xin,
Lin ZheShuai,
Chen Yong,
Fu WenFu
Publication year - 2017
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201700584
Subject(s) - chemistry , nitrile , ammonia borane , nitro , catalysis , primary (astronomy) , borane , selectivity , reactivity (psychology) , ammonia , homogeneous catalysis , organic chemistry , combinatorial chemistry , hydrogen production , medicine , alkyl , physics , alternative medicine , pathology , astronomy
Selective hydrogenation of nitrile groups to primary amines is challenging owing to their high reactivity towards producing secondary and tertiary amines. An unprecedented and efficient system for the hydrogenation of nitrile and nitro groups to primary amines catalyzed by Ni 2 P nanoparticles in mixed aqueous H 3 NBH 3 solution under ambient conditions is reported. The system exhibits high catalytic selectivity towards generating primary amines, resulting in good isolated yields. Density functional theory calculations rationalize the observed results that composite interactions among species on the catalyst surface alter the catalytic pathway. More information can be found in the Communication by Wen‐Fu Fu et al. on page 1589 in Issue 11, 2017 (DOI: 10.1002/ajoc.201700383).