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Pd‐Catalyzed Cyclopropanation Reaction of Aliphatic Ketones with Monosubstituted Allyl Reagents
Author(s) -
Huang JianQiang,
Zhao JingFeng,
Yang Zhen,
Ding ChangHua,
Hou XueLong,
Peng XiaoShui,
Wong Henry Nai Ching
Publication year - 2017
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201700541
Subject(s) - cyclopropanation , chemistry , cyclopropane , catalysis , nucleophile , reagent , pyridine , selectivity , ligand (biochemistry) , medicinal chemistry , organic chemistry , ring (chemistry) , biochemistry , receptor
A Pd‐catalyzed cyclopropanation reaction with aliphatic ketones as nucleophiles using a modified pyridine‐NHC ligand was achieved. The reaction afforded the corresponding cyclopropanes in moderate to good yields with high cyclopropane/allylation selectivity.