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Ru(bpy) 3 Cl 2 as a Photocatalyst for Visible‐Light‐Induced Fluoroalkylation of Anilines with BrCF 2 CF 2 Br: A Facile Route to 2‐Bromo‐1,1,2,2‐tetrafluoroethyl Arenes
Author(s) -
Kong Jingjing,
Jiang Jianfang,
Huang Yang,
Lou YueGuang,
Li XiaoFei,
He ChunYang
Publication year - 2017
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201700422
Subject(s) - chemistry , reagent , photocatalysis , combinatorial chemistry , irradiation , catalysis , photochemistry , organic chemistry , physics , nuclear physics
A convenient method for the preparation of 2‐bromo‐1,1,2,2‐tetrafluoroethyl arenes, using commercially available anilines and BrCF 2 CF 2 Br as starting materials was developed. The reaction proceeded in high efficiency under the irradiation of blue LEDs, and enables the installation of amino and fluoroalkyl moieties. Moreover, the product can be easily transformed to many other 1,1,2,2‐tetrafluoroethylated reagents, thus demonstrating its high potential use for further modifications.