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Synthesis of Indolizine‐Containing Diaryl‐ and Triarylmethanes through a Cu‐Catalyzed Domino Cyclization of 2‐(2‐Enynyl)pyridines
Author(s) -
Mahesh Sriram,
Paluru Dilip K.,
Ahmad Feroz,
Patil Swati,
Kant Guddi,
Anand Ramasamy Vijaya
Publication year - 2017
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201700419
Subject(s) - chemistry , indolizine , domino , catalysis , hydride , nucleophile , medicinal chemistry , combinatorial chemistry , organic chemistry , hydrogen
A Cu‐catalyzed protocol for the synthesis of indolizine‐containing diaryl‐ and triarylmethane derivatives through a 5‐ endo ‐ dig cyclization of 2‐(2‐enynyl)pyridines, followed by a remote addition of nucleophiles, such as hydride and 2‐naphthols, is described.
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