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Robust Hydrogenation of Nitrile and Nitro Groups to Primary Amines Using Ni 2 P as a Catalyst and Ammonia Borane under Ambient Conditions
Author(s) -
Zen YunFeng,
Fu ZiCheng,
Liang Fei,
Xu Yong,
Yang DanDan,
Yang Zhi,
Gan Xin,
Lin ZheShuai,
Chen Yong,
Fu WenFu
Publication year - 2017
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201700383
Subject(s) - nitrile , chemistry , ammonia borane , nitro , catalysis , primary (astronomy) , selectivity , borane , ammonia , organic chemistry , combinatorial chemistry , nitro compound , hydrogen production , alkyl , physics , astronomy
The selective hydrogenation of nitrile groups to primary amines is challenging owing to their high ability to produce secondary and tertiary amines. Herein, we report an efficient system for the hydrogenation of nitrile and nitro groups to primary amines catalyzed by Ni 2 P nanoparticles in an aqueous H 3 NBH 3 solution under ambient conditions. The system exhibits high catalytic selectivity toward generating primary amines, resulting in good isolated yields. A combination of experiments and theoretical calculations shows that composite interactions among species on the catalyst surface alter the catalytic pathway.