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Copper‐Catalyzed C−H Activation of Substituted Pyridines Leading to Imidazopyridine Derivatives via Self‐Redox of the Substrates
Author(s) -
Lou Zhenbang,
Yang Haijun,
Zhu Changjin,
Fu Hua
Publication year - 2017
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201700381
Subject(s) - chemistry , imidazopyridine , redox , catalysis , copper , aryl , base (topology) , combinatorial chemistry , pyridine , dabco , organic chemistry , medicinal chemistry , alkyl , mathematical analysis , mathematics
A simple and practical copper‐catalyzed C−H activation of substituted pyridines with O‐aryl oximes leading to imidazo[1,2‐ a ]pyridines has been developed via self‐redox of the substrates. The reaction performed well under mild conditions, tolerating many functional groups. Importantly, the C−H activation did not need an added oxidant, additive, acid or base.

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