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Silver‐Catalyzed Synthesis of Substituted Carbazoles through a Tandem Intramolecular Hydroamination/Cyclization Sequence
Author(s) -
Purnachandar Dalovai,
Suneel Kanaparthy,
Sridhar Balasubramanian,
Karunakar Galla V.
Publication year - 2017
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201700379
Subject(s) - hydroamination , chemistry , carbazole , intramolecular force , catalysis , tandem , combinatorial chemistry , sequence (biology) , medicinal chemistry , organic chemistry , materials science , composite material , biochemistry
A silver‐catalyzed synthesis of substituted carbazoles from 2‐(6‐substituted‐3‐hexanol‐1,5‐diynyl)anilines has been achieved. In this transformation, new C−C and C−N bonds were formed through a hydroamination reaction, followed by cyclization. The carbazole derivatives were obtained in good‐to‐excellent yields in a one‐pot synthesis at ambient temperature.

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