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Ruthenium‐Catalyzed Oxidative Annulation of Anilines using Benzothiazole as a Removable Directing Group
Author(s) -
Sharma Shivani,
Singh Sukanya,
Kumari Akhilesh,
Sawant Devesh M.,
Pardasani Ram T.
Publication year - 2017
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201700098
Subject(s) - benzothiazole , chemistry , annulation , ruthenium , catalysis , cationic polymerization , oxidative phosphorylation , group (periodic table) , combinatorial chemistry , scope (computer science) , organic chemistry , aniline , biochemistry , computer science , programming language
An efficient and inexpensive cationic ruthenium(II) catalyst enabled synthesis of bis‐heterocycles through an oxidative annulation of benzothiazole‐directed anilines and alkynes is described. This strategy provides a broad scope of anilines bearing a directing group and alkynes with good to excellent yields. To our knowledge, this is the first report on benzothiazoles as removable directing groups, leading to the construction of diversified indoles.