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Cover Picture: Photocatalytic Trifluoromethylthiolation of Aromatic Alkenes Associated with Hydroxylation and Alkoxylation (Asian J. Org. Chem. 4/2017)
Author(s) -
Li Yanjie,
Koike Takashi,
Akita Munetaka
Publication year - 2017
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201700003
Subject(s) - chemistry , reagent , regioselectivity , electrophile , hydroxylation , photocatalysis , electrophilic aromatic substitution , pyrrolidine , catalysis , photochemistry , organic chemistry , combinatorial chemistry , enzyme
Single‐electron‐transfer (SET) process : The photoactivated Ir catalyst fac ‐[Ir(4‐MeO‐ppy) 3 ] (4‐MeO‐ppy=2‐pyridyl‐5‐methoxyphenyl) is useful for one‐electron reduction of the electrophilic CF 3 S reagent 1‐(trifluoromethylthio)pyrrolidine‐2,5‐dione, resulting in the formation of a trifluoromethansulfenyl radical. This is a new strategy for the activation of the electrophilic CF 3 S reagent. The well‐designed photoredox system allow for single‐step, regioselective oxy‐trifluoromethylthiolation of aromatic alkenes with no need of additives for the activation of the CF 3 S reagent. More information can be found in the Communication by Takashi Koike, Munetaka Akita, and Yanjie Li on page 445 in Issue 4, 2017 (DOI: 10.1002/ajoc.201600562).