Premium
Cobalt‐Catalyzed Alkylation–Peroxidation of Alkenes with 1,3‐Dicarbonyl Compounds and T‐Hydro
Author(s) -
Lu Shenglin,
Qi Longying,
Li Zhiping
Publication year - 2017
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201600608
Subject(s) - chemistry , cobalt , alkylation , catalysis , organic chemistry , combinatorial chemistry , organic synthesis , medicinal chemistry
A method for the cobalt‐catalyzed alkylation–peroxidation of alkenes with 1,3‐dicarbonyl compounds and T‐hydro ( tert ‐butyl hydroperoxide solution) was developed. This approach provides practical and selective access to γ‐carbonyl peroxides in a single step by starting from readily available starting materials. In addition, gram‐scale syntheses demonstrated that the protocol is practical and useful for organic synthesis.