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Cover Picture: Selective Recognition and Quantification of 2,3‐Bisphosphoglycerate in Human Blood Samples by a Rhodamine Derivative (Asian J. Org. Chem. 1/2017)
Author(s) -
Sarkar Himadri Sekhar,
Das Sujoy,
Uddin Md Raihan,
Mandal Sukhendu,
Sahoo Prithidipa
Publication year - 2017
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201600556
Subject(s) - chemistry , derivative (finance) , cover (algebra) , rhodamine , human blood , chromatography , fluorescence , optics , mechanical engineering , physiology , physics , financial economics , engineering , economics , biology
OFF! ON! OFF ! 2,3‐bisphosphoglycerate ( 2,3‐BPG ) facilitates oxygen release from the erythrocyte to the surrounding tissues by preferentially binding to deoxyhemoglobin. A new chemosensing ensemble of an azo‐based rhodamine derivative with Hg 2+ has been developed for a selective and quantitative detection of 2,3‐BPG , which shows a simple dual signal (color and “off‐on‐off” fluorescent change) in live cell and human blood sample at a very low concentration. The probe may be used to develop a new generation of 2,3‐BPG detection kit applicable for diseases like hypoxia, high altitude pulmonary edema, hyperthyroidism, congestive heart failure, etc. More information can be found in the Communication by Prithidipa Sahoo et al. on page 71 in Issue 1, 2017 (DOI: 10.1002/ajoc.201600516).