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Synthesis of Tetrasubstituted Furans by Using Photoredox‐Catalyzed Coupling of 2‐Bromo‐1,3‐dicarbonyl Compounds with Silyl Enol Ethers
Author(s) -
Han YueYue,
Jiao YanYan,
Ren Daan,
Hu Zhentao,
Shen Sheng,
Yu Shouyun
Publication year - 2017
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201600489
Subject(s) - chemistry , enol , aromatization , silylation , photoredox catalysis , catalysis , combinatorial chemistry , organic chemistry , photocatalysis
Abstract A practical and efficient method has been developed for the preparation of polysubstituted furans by using a visible‐light‐promoted photoredox approach. The one‐pot synthesis involves a radical cyclization/deprotection/aromatization reaction sequence that proceeds smoothly under mild conditions, which makes this transformation a powerful tool for the synthesis of a variety of highly substituted furans.