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Phosphine–Thiourea‐Organocatalyzed Asymmetric C−N and C−S Bond Formation Reactions
Author(s) -
Ngo ThiThuyDuong,
Nguyen ThiHuong,
Bournaud Chloée,
Guillot Régis,
Toffano Martial,
VoThanh Giang
Publication year - 2016
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201600212
Subject(s) - chemistry , thiourea , phthalimide , phosphine , organocatalysis , medicinal chemistry , alkyl , adduct , organic chemistry , baylis–hillman reaction , enantioselective synthesis , catalysis
Phosphine–thiourea based‐organocatalysts derived from l ‐proline promoted C−N or C−S bond formation of tert ‐butoxycarbonyloxy‐Morita—Baylis—Hillman adducts with phthalimide or alkyl thiols, respectively. Good yields and enantioselectivities up to 93 % were achieved.