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Palladium‐Catalyzed Direct Benzylation of Polyfluoroarenes with Benzyl Carbonates through Selective C−H Functionalization
Author(s) -
Yang Guanghui,
Jiang Xinpeng,
Liu Yong,
Li Na,
Yin Guisen,
Yu Chuanming
Publication year - 2016
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201600204
Subject(s) - chemistry , surface modification , palladium , catalysis , combinatorial chemistry , organic chemistry
A novel and efficient palladium‐catalyzed cross‐coupling benzylation reaction of pentafluorobenzene through selective C−H functionalization has been developed. A series of carbonates and polyfluorobenzenes have been examined and found to give moderate to good yields. This transformation provides a new straightforward approach for the synthesis of fluorinated diarylmethanes.