Premium
Cover Picture: Carbonylation of Csp 3 −H Bonds through Oxidative Wittig‐Type Reaction: An Unprecedented Version of Wittig Reaction (Asian J. Org. Chem. 5/2016)
Author(s) -
Zhu Yingzu,
Lü Shiwei,
Ma Xingge,
Zhang Liang,
Luo Liangliang,
Jia Xiaodong
Publication year - 2016
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201600127
Subject(s) - wittig reaction , chemistry , carbonylation , triple bond , medicinal chemistry , organic chemistry , double bond , photochemistry , catalysis , carbon monoxide
An oxidative Wittig‐type reaction was developed. The classical Wittig reaction is one of the most powerful synthetic tools for construction of carbon–carbon double bonds from carbonyls, but here comes a surprising version, in which carbonyl groups are installed by similar process. The mechanism shows that the reaction is mediated by an oxo‐four‐membered intermediate, which looks like a humorous face. More information can be found in the communication by X. Jia and co‐workers on page 617 in Issue 5, 2016 (DOI: 10.1002/ajoc.201600055).