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Chiral Recognition of Carboxylates—Receptors, Analytical Tools, and More
Author(s) -
Ulatowski Filip,
Jurczak Janusz
Publication year - 2016
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201600093
Subject(s) - chemistry , molecular recognition , receptor , enantiomer , chirality (physics) , combinatorial chemistry , nanotechnology , molecule , computational biology , biochemical engineering , stereochemistry , organic chemistry , biochemistry , engineering , materials science , physics , biology , nambu–jona lasinio model , chiral symmetry breaking , quantum mechanics , quark
Most carboxylic acids, which are among the most common molecules in biological systems, are chiral. The enantiomers of these species are commonly distinguished in nature, but such recognition has proven quite difficult to reproduce by using artificial receptors. Better knowledge of the chiral recognition of carboxylates is therefore crucial for a full understanding of host–guest phenomena in nature, and also for the design of new analytical devices. In this Focus Review we summarize and discuss the methods employed to evaluate receptors, and present a variety of structural designs that have been utilized in chiral receptors. Some advanced functions of receptors in sensors and sensor arrays are also reviewed.