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Chiral Brønsted Acid Catalyzed Kinetic Resolutions
Author(s) -
Petersen Kimberly S.
Publication year - 2016
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201600021
Subject(s) - kinetic resolution , chemistry , catalysis , kinetic energy , organic molecules , molecule , brønsted–lowry acid–base theory , small molecule , combinatorial chemistry , enantioselective synthesis , organic synthesis , chirality (physics) , organic chemistry , computational chemistry , biochemistry , physics , quantum mechanics , chiral symmetry breaking , quark , nambu–jona lasinio model
The synthesis of enantioenriched small molecules is an ongoing goal of organic chemists. This Focus Review explores the use of kinetic resolutions catalyzed by chiral Brønsted acids. Methods include classic kinetic resolutions and dynamic kinetic resolutions. The small molecules obtained are potentially valuable intermediates in the synthesis of biologically important compounds.
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