Cover Picture: An Efficient One‐Pot Five‐Component Tandem Sequential Approach for the Synthesis of Pyranopyrazole Derivatives via Suzuki Coupling and Multicomponent Reaction (Asian J. Org. Chem. 5/2015)

Multicomponent reactions (MCRs) have emerged as a powerful tool for the construction of novel and complex molecular structures due to their advantages over conventional multistep synthesis. In their Full Paper on page 487 , Yiqun Li and co‐workers have developed a one‐pot, tandem, sequential, five component reaction (5CR) protocol for the synthesis of a wide range of biaryl‐substituted pyranopyrazole derivatives via Suzuki coupling of 4‐bromobenzaldehyde and phenylbronic acids followed by four‐component reaction of ethyl acetoacetate, malononitrile, and hydrazine hydrate without isolation and/or purification of intermediates.