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Cover Picture: Photoaffinity Probes for Identification of Carbohydrate‐Binding Proteins (Asian J. Org. Chem. 2/2015)
Author(s) -
Sakurai Kaori
Publication year - 2015
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201590002
Subject(s) - photoaffinity labeling , chemistry , carbohydrate , identification (biology) , biochemistry , computational biology , binding site , biology , botany
Carbohydrates play important biological roles by mediating cellular signals through interacting with proteins. However, many carbohydrate‐protein interactions remain unknown due to the inherent difficulties in studying them. Photoaffinity labeling offers a promising chemical strategy for the identification of carbohydrate‐binding proteins in their native environment. In her Focus Review on page 116, Kaori Sakurai highlights recent examples of carbohydrate photoaffinity probes, which have been designed to address challenges associated in capturing often elusive carbohydrate‐binding proteins. Photo credit: Sho Narita and Shimpei Ozawa.