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Synthesis of Functionalized 2‐Trifluoromethylquinolines and their Heteroaromatic Analogues
Author(s) -
Khutoryanskiy Viktor V.,
Biitseva Angelina V.,
Mykhailiuk Pavel K.
Publication year - 2016
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201500519
Subject(s) - chemistry , carbamate , protecting group , combinatorial chemistry , organic chemistry , stereochemistry , alkyl
Electron‐rich anilines and amino heterocycles were converted in one step into N ‐protected functionalized aminoethyl 2‐trifluoromethylquinolines and their heteroaromatic analogues. The N‐carbamate protecting group can be easily cleaved under acidic conditions to give the corresponding amines.