Premium
Palladium‐Catalyzed Double Ullmann Reaction: An Approach towards Tetraphenylenes
Author(s) -
Li Xin,
Han JianWei,
Wong Henry N. C.
Publication year - 2016
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201500327
Subject(s) - palladium , chemistry , catalysis , coupling reaction , double bond , combinatorial chemistry , organic chemistry
A palladium‐catalyzed double Ullmann coupling reaction for the preparation of tetraphenylenes has been developed. With this protocol, twelve tetraphenylene derivatives were synthesized from the corresponding 2,2′‐diiodobiaryls directly with the yields ranging from 13–51 %. Insights into the mechanism of these palladium‐catalyzed double coupling reactions are discussed, and the findings are expected to increase the level of understanding of palladium‐catalyzed formation of carbon–carbon bonds within rigid molecular frameworks.