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Efficient Palladium‐Catalyzed Synthesis of Sulfonyl‐Substituted Vinyl Arenes: Hydrazones Provide the Cross‐Coupling Partner and Nucleophile Components
Author(s) -
Wu XinXing,
Chen Si,
Chen WenLong,
Wang LiJing,
Gao Pin,
Xu PengFei,
Liang YongMin
Publication year - 2015
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201500092
Subject(s) - chemistry , nucleophile , sulfonyl , aryl , halide , palladium , catalysis , atom economy , coupling (piping) , coupling reaction , combinatorial chemistry , organic chemistry , polymer chemistry , mechanical engineering , alkyl , engineering
A practical and efficient approach for the synthesis of various sulfonyl‐substituted vinyl arenes is reported. In the process, hydrazones provide coupling partners for the Pd‐catalyzed cross‐coupling with aryl halides and sulfinate salts as nucleophiles, which realizes minimal waste and excellent atom economy.