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Spin‐Labelling of Host‐Guest Assemblies with Nitroxide Radicals
Author(s) -
Mezzina Elisabetta,
Mai Roberta,
Romano Francesco,
Lucarini Marco
Publication year - 2015
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201402286
Subject(s) - nitroxide mediated radical polymerization , chemistry , radical , supramolecular chemistry , electron paramagnetic resonance , covalent bond , host–guest chemistry , molecule , site directed spin labeling , nanotechnology , photochemistry , combinatorial chemistry , monomer , organic chemistry , polymer , nuclear magnetic resonance , radical polymerization , materials science , physics
Within the developing interface between free radicals and supramolecular chemistry, nitroxides play a special role because they are stable and easy to functionalize. This Focus Review summarizes recent progress in the design and synthesis of paramagnetic host‐guest complexes characterized by the presence of a nitroxide label covalently linked to the organic macrocycle. Examples include the synthesis of open‐shell, mechanically interlocked molecules (MIMs), such as rotaxanes, in which the dumbbell, the wheel, or both are tagged with nitroxide radicals, and how electron spin resonance (ESR) spectroscopy methods have been used for detecting and identifying the assemblies and for clarifying their structure and properties.