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Supramolecular Catalysis in the Synthesis of Substituted 1 H ‐Tetrazoles from Isonitriles by a Self‐Assembled Hexameric Capsule
Author(s) -
Giust Sonia,
La Sorella Giorgio,
Sperni Laura,
Fabris Fabrizio,
Strukul Giorgio,
Scarso Alessandro
Publication year - 2015
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201402229
Subject(s) - chemistry , supramolecular chemistry , trimethylsilyl azide , catalysis , reagent , supramolecular catalysis , trimethylsilyl , azide , combinatorial chemistry , calixarene , self assembly , substrate (aquarium) , stereochemistry , organic chemistry , molecule , oceanography , geology
The synthesis of substituted 1 H ‐tetrazoles from aliphatic or aromatic isonitriles and trimethylsilyl azide can be efficiently promoted by the hexameric capsule of resorcin[4]arene as a supramolecular self‐assembled catalyst. The reaction is sensitive to the size and nature of the substrate and is driven by encapsulation of the reagents within the cavity of the supramolecular catalyst.