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Synthesis of Fused Quinoline and Quinoxaline Derivatives Enabled by Domino Radical Triple Bond Insertions
Author(s) -
Sun Xiaoyang,
Li Jiahong,
Ni Yunpeng,
Ren Daan,
Hu Zhentao,
Yu Shouyun
Publication year - 2014
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201402222
Subject(s) - quinoxaline , chemistry , quinoline , domino , regioselectivity , triple bond , combinatorial chemistry , environmentally friendly , organic chemistry , double bond , catalysis , ecology , biology
A practical and environmentally friendly strategy for the preparation of fused quinoline and quinoxaline derivatives has been developed, enabled by domino radical triple bond insertions. These reactions have very high regioselectivity and can be carried out under mild conditions in good to excellent chemical yields.