Efficient Copper Catalyzed CN Coupling Reaction in Water by Using 2‐Hydroxybenzohydrazides as Ligands | Zendy

Yan NanNan | Zendy; Wu FengTian | Zendy; Zhang Jie | Zendy; Wei QianBing | Zendy; Liu Ping | Zendy; Xie JianWei | Zendy; Dai Bin | Zendy

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Efficient Copper Catalyzed CN Coupling Reaction in Water by Using 2‐Hydroxybenzohydrazides as Ligands

Author(s) -

Yan NanNan,

Wu FengTian,

Zhang Jie,

Wei QianBing,

Liu Ping,

Xie JianWei,

Dai Bin

Publication year - 2014

Publication title -

asian journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.846

H-Index - 44

eISSN - 2193-5815

pISSN - 2193-5807

DOI - 10.1002/ajoc.201402136

Subject(s) - chemistry , halide , nucleophile , catalysis , aryl , ligand (biochemistry) , environmentally friendly , copper , combinatorial chemistry , nitrogen , coupling reaction , organic chemistry , ecology , biochemistry , alkyl , receptor , biology

An efficient and environmentally friendly protocol has been developed for CuSO 4 ‐catalyzed N ‐arylation of nitrogen‐containing nucleophiles with aryl halides in water. The method uses 2‐hydroxybenzohydrazides as ligand, avoids the use of organic solvents, and tolerates functional groups well.

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