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Synthesis of 19‐Nor‐Vitamin D A‐Ring Synthons via Ring‐Closing Olefin Metathesis
Author(s) -
Nagai Yu,
Tanami Tomoe,
Abe Junko,
Nagai Hazuki,
Hamamizu Toru,
Kominato Kaichiro,
Iida Keisuke,
Nagasawa Kazuo
Publication year - 2014
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201402109
Subject(s) - chemistry , synthon , ring closing metathesis , olefin metathesis , ring (chemistry) , closing (real estate) , olefin fiber , stereochemistry , metathesis , organic chemistry , combinatorial chemistry , catalysis , political science , law , polymerization , polymer
19‐Nor‐vitamin D A‐ring synthons were obtained from linear olefins by means of ring‐closing olefin metathesis followed by palladium‐catalyzed isomerization of the endocyclic olefin product to an exocyclic olefin.