Premium
Fluorescent Probes for Hydrogen Sulfide Detection
Author(s) -
Peng Bo,
Xian Ming
Publication year - 2014
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201402064
Subject(s) - hydrogen sulfide , chemistry , fluorescence , nanotechnology , computational biology , biophysics , combinatorial chemistry , biology , organic chemistry , sulfur , physics , materials science , quantum mechanics
Hydrogen sulfide (H 2 S) is an important signaling molecule with potent cytoprotective actions. Current results strongly suggest that modulation of H 2 S levels could have potential therapeutic values for a number of disease states, but its exact mechanisms of action are still unclear. A number of fundamental issues must be addressed to advance our understanding of the biology and clinical potential of H 2 S in the future. It is important, therefore, to understand the chemistry and properties of H 2 S and to appreciate the limitation and errors that may be generated when measuring H 2 S in biological samples. In the past several years a number of fluorescent probes for H 2 S detection have been developed. These probes are based on H 2 S‐mediated reactions and are useful research tools. Herein, we provide an overview of current progress in this field. The development and properties of representative probes are discussed.