Organocatalytic Asymmetric Condensation/Keto–Enol Tautomerization Tandem Reaction: Access to Cyclobutanone α‐Amino Acid Ester Derivatives | Zendy

Frongia Angelo | Zendy; Melis Nicola | Zendy; Serra Ilaria | Zendy; Secci Francesco | Zendy; Piras Pier Paolo | Zendy; Caboni Pierluigi | Zendy

Premium

Organocatalytic Asymmetric Condensation/Keto–Enol Tautomerization Tandem Reaction: Access to Cyclobutanone α‐Amino Acid Ester Derivatives

Author(s) -

Frongia Angelo,

Melis Nicola,

Serra Ilaria,

Secci Francesco,

Piras Pier Paolo,

Caboni Pierluigi

Publication year - 2014

Publication title -

asian journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.846

H-Index - 44

eISSN - 2193-5815

pISSN - 2193-5807

DOI - 10.1002/ajoc.201400020

Subject(s) - chemistry , tautomer , enol , optically active , cyclobutanone , amino acid , tandem , cascade reaction , enantioselective synthesis , condensation , organic chemistry , alkyl , condensation reaction , organocatalysis , catalysis , combinatorial chemistry , ring (chemistry) , biochemistry , materials science , physics , composite material , thermodynamics

A practical method for the synthesis of optically active α‐amino cyclobutanones has been developed, via an organocatalytic asymmetric condensation reaction between racemic 2‐hydroxycyclobutanone and chiral N ‐alkyl‐α‐amino acid ester derivatives.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research