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Inside Cover: Redox Potential of Nitroxides is an Index to Evaluate Superoxide Dismutase Mimic Activity (Asian J. Org. Chem. 5/2013)
Author(s) -
Yamasaki Toshihide,
Matsuoka Yuta,
Mito Fumiya,
Yamato Mayumi,
Yamada Kenichi
Publication year - 2013
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201390013
Subject(s) - chemistry , nitroxide mediated radical polymerization , redox , superoxide dismutase , superoxide , piperidine , photochemistry , combinatorial chemistry , stereochemistry , antioxidant , organic chemistry , enzyme , radical polymerization , copolymer , polymer
Redox Chemistry Nitroxides are organic spin compounds that are used as antioxidants because of their ability to react with superoxide. In their Communication on page 388 ff. featured on the inside cover, Ken‐ichi Yamada and co‐workers evaluate the effect of changing the C4 substituents on the redox potential of piperidine nitroxides with the aim of identifying a good index for developing better superoxide dismutase (SOD) mimics. The redox potential of a nitroxide/ N ‐oxoammonium cation couple correlates strongly with their reactivity towards superoxide. Thus, the SOD‐mimicking activity of a nitroxide can be controlled based on its redox potential.