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C 2 ‐Symmetric Homobimetallic Zinc Complexes as Chiral Catalysts for the Highly Enantioselective Hydrophosphonylation of Aldehydes
Author(s) -
Sun Lin,
Guo QiPeng,
Li Xiao,
Zhang Lei,
Li YuYan,
Da ChaoShan
Publication year - 2013
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201300181
Subject(s) - chemistry , zinc , enantioselective synthesis , bifunctional , catalysis , alkoxide , organic chemistry , yield (engineering) , lewis acids and bases , combinatorial chemistry , metallurgy , materials science
Zinc in the pink : The first zinc‐catalyzed asymmetric hydrophosphonylation of aldehydes is demonstrated with high enantioselectivity and yield. The bifunctional catalyst is a homobimetallic zinc complex, in which one zinc alkoxide group serves as the Brønsted base to activate the phosphite and the other as the Lewis acid to activate aldehydes.