Enantioselective Transfer Hydrogenation of Difluoromethyl Ketimines Using Benzothiazoline as a Hydrogen Donor in Combination with a Chiral Phosphoric Acid | Zendy

Sakamoto Tsubasa | Zendy; Horiguchi Kosaku | Zendy; Saito Kodai | Zendy; Mori Keiji | Zendy; Akiyama Takahiko | Zendy

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Enantioselective Transfer Hydrogenation of Difluoromethyl Ketimines Using Benzothiazoline as a Hydrogen Donor in Combination with a Chiral Phosphoric Acid

Author(s) -

Sakamoto Tsubasa,

Horiguchi Kosaku,

Saito Kodai,

Mori Keiji,

Akiyama Takahiko

Publication year - 2013

Publication title -

asian journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.846

H-Index - 44

eISSN - 2193-5815

pISSN - 2193-5807

DOI - 10.1002/ajoc.201300174

Subject(s) - enantioselective synthesis , chemistry , phosphoric acid , transfer hydrogenation , organic chemistry , hydrogen , catalysis , combinatorial chemistry , ruthenium

Hold the benzothiazoline : Highly enantioselective transfer hydrogenation of difluoromethyl ketimines with benzothiazolines catalyzed by a chiral phosphoric acid furnishes α‐difluoromethylated amines in good yields and with excellent enantioselectivity, irrespective of the stereochemistry of the starting materials. PMP= p ‐methoxyphenyl.

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