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An Enantiodivergent Synthesis of (+)‐ and (−)‐Centrolobines by Asymmetric Esterification Catalyzed by ( R )‐(+)‐ N ‐Methylbenzoguanidine (( R )‐NMBG)
Author(s) -
Nakata Kenya,
Tokumaru Tatsuya,
Iwamoto Hidetoshi,
Nishigaichi Yutaka,
Shiina Isamu
Publication year - 2013
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201300139
Subject(s) - chemistry , catalysis , enantioselective synthesis , heaven , stereochemistry , key (lock) , organic chemistry , medicinal chemistry , theology , ecology , philosophy , biology
Seventh heaven : The enantiodivergent synthesis of (+)‐ and (−)‐centrolobines was achieved in a total of seven steps by using an asymmetric esterification in the presence of catalytic ( R )‐(+)‐ N ‐methylbenzoguanidine as the key reaction.
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