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Direct CH Arylation of Unactivated Arenes with Aryl Halides Promoted by Bis(imino)pyridine Derivatives
Author(s) -
A Sigen,
Liu Xiaoming,
Li He,
He Chuanyi,
Mu Ying
Publication year - 2013
Publication title -
asian journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 44
eISSN - 2193-5815
pISSN - 2193-5807
DOI - 10.1002/ajoc.201300129
Subject(s) - chemistry , pyridine , halide , aryl , transition metal , medicinal chemistry , potassium , organic chemistry , combinatorial chemistry , catalysis , alkyl
A new class of multichelating bis(imino)pyridine compounds can promote the direct arylation of unactivated arene CH bonds with aryl iodides and bromides in the presence of potassium tert ‐butoxide. This transition‐metal‐free process provides a promising system for cheap and efficient synthesis of biaryl structural units.