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Implementing individualized medicine into the medical practice
Author(s) -
Lazaridis Konstantinos N.,
M Tammy M.,
BabovicVuksanovic Dusica,
Beck Scott A.,
Borad Mitesh J.,
Bryce Alan H.,
ChananKhan Asher A.,
Ferber Matthew J.,
Fonseca Rafael,
Johnson Kiley J.,
Klee Eric W.,
Lindor Noralane M.,
M Jennifer B.,
M Robert R.,
Parker Alexander S.,
RiegertJohnson Douglas L.,
Rohrer Vitek Carolyn R.,
Schahl Kimberly A.,
Schultz Cloann,
Stewart Keith,
Then George C.,
Wieben Eric D.,
Farrugia Gianrico
Publication year - 2014
Publication title -
american journal of medical genetics part c: seminars in medical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.419
H-Index - 101
eISSN - 1552-4876
pISSN - 1552-4868
DOI - 10.1002/ajmg.c.31387
Subject(s) - personalized medicine , genomic medicine , precision medicine , workflow , medicine , genomics , health care , mainstream , translational medicine , alternative medicine , medical education , bioinformatics , computer science , computational biology , genome , pathology , biochemistry , chemistry , philosophy , theology , database , gene , economics , biology , economic growth
There is increasing recognition that genomic medicine as part of individualized medicine has a defined role in patient care. Rapid advances in technology and decreasing cost combine to bring genomic medicine closer to the clinical practice. There is also growing evidence that genomic‐based medicine can advance patient outcomes, tailor therapy and decrease side effects. However the challenges to integrate genomics into the workflow involved in patient care remain vast, stalling assimilation of genomic medicine into mainstream medical practice. In this review we describe the approach taken by one institution to further individualize medicine by offering, executing and interpreting whole exome sequencing on a clinical basis through an enterprise‐wide, standalone individualized medicine clinic. We present our experience designing and executing such an individualized medicine clinic, sharing lessons learned and describing early implementation outcomes. © 2014 Wiley Periodicals, Inc.