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Clinical considerations in gastroschisis: Incremental advances against a congenital anomaly with severe secondary effects
Author(s) -
Nichol Peter F.,
Byrne Janice L.B.B.,
Dodgion Christopher,
Saijoh Yukio
Publication year - 2008
Publication title -
american journal of medical genetics part c: seminars in medical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.419
H-Index - 101
eISSN - 1552-4876
pISSN - 1552-4868
DOI - 10.1002/ajmg.c.30180
Subject(s) - gastroschisis , anomaly (physics) , medicine , biology , pregnancy , genetics , fetus , physics , condensed matter physics
Gastroschisis is one of the most challenging congenital anomalies that physicians treat in the first 2 months of life. Over the last 40 years, tremendous progress has been made in the management of this defect. Survival has increased significantly during this period as well. However, gastroschisis still presents the clinician with a unique set of challenges as a result of secondary effects on intestinal development. These challenges or clinical considerations are discussed in this review including a history of the management of the defect, prenatal counseling, prenatal intervention, postnatal and surgical management, complications and long‐term outcomes. © 2008 Wiley‐Liss, Inc.