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No association between DUP25 and anxiety disorders
Author(s) -
Henrichsen Charlotte Neergaard,
Delorme Richard,
Boucherie Maria,
Marelli Dominique,
Baud Patrick,
Bellivier Franck,
Courtet Philippe,
Chabane Nadia,
Henry Chantal,
Leboyer Marion,
Malafosse Alain,
Antonarakis Stylianos E.,
Dahoun Sophie
Publication year - 2004
Publication title -
american journal of medical genetics part b: neuropsychiatric genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.393
H-Index - 126
eISSN - 1552-485X
pISSN - 1552-4841
DOI - 10.1002/ajmg.b.30037
Subject(s) - anxiety , panic , dup , gene duplication , psychology , population , panic disorder , clinical psychology , association (psychology) , psychiatry , medicine , psychotherapist , genetics , biology , gene , environmental health
Abstract Gratacos et al. [2001: Cell 106:367‐379] described an interstitial duplication dup(15)q24q26 (DUP25) in patients with anxiety disorders; this duplication was found in approximately 90% of patients and in 7% of controls. In order to determine if DUP25 is present in additional individuals susceptible to panic attacks, we tested 44 patients with anxiety disorders, using probes 251c23 and 216c14 mapping in the 15q24 and 15q26 region. We have not detected any DUP25. Our results suggest that DUP25 is not common in people with anxiety disorders in the population tested here. © 2004 Wiley‐Liss, Inc.