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Elucidating the role of genetic factors in smoking behavior and nicotine dependence
Author(s) -
Lerman Caryn,
Berrettini Wade
Publication year - 2003
Publication title -
american journal of medical genetics part b: neuropsychiatric genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.393
H-Index - 126
eISSN - 1552-485X
pISSN - 1552-4841
DOI - 10.1002/ajmg.b.10003
Subject(s) - addiction , nicotine , nicotine dependence , smoking cessation , nicotine addiction , genomics , tobacco control , population , psychology , psychiatry , medicine , biology , environmental health , public health , genetics , genome , nursing , pathology , gene
Despite over a decade of intensive tobacco control efforts, a substantial proportion of the world's population continues to smoke. With advances in molecular biology and genomics technology, attention is focusing on the genetic basis of addiction to nicotine. The hope is that by better understanding the biology of nicotine addiction, novel prevention and cessation strategies can be developed and targeted to individuals most likely to benefit. This article provides an overview of currently available data from genetics research on smoking behavior and discusses study design issues to be addressed to make progress in this line of research. © 2003 Wiley‐Liss, Inc.