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Vascular twin nevi
Author(s) -
Agirgol Senay,
Ozturk Hatice Nur,
Akbulut Tugba Ozkok,
Gunduzoglu Ceyda,
Koc Leyli Kadriye,
Turkoglu Zafer
Publication year - 2017
Publication title -
american journal of medical genetics part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.064
H-Index - 112
eISSN - 1552-4833
pISSN - 1552-4825
DOI - 10.1002/ajmg.a.38117
Subject(s) - vascular anomaly , nevus , somatic cell , mitosis , biology , medicine , dermatology , pathology , melanoma , genetics , gene , psychiatry
Vascular twin nevi (VTN) are characterized by the simultaneous dermatological manifestatiton of a telangiectatic naevus close to a nevus anemicus. Nevus anemicus (NA) is a vascular anomaly characterized by localized pale patches with normal melanine and melanocyte level. According to twin spotting phenomenon crossing‐over in heterozygous somatic‐cells during mitosis results in two different offspring homozygous cells. Consequent to this mechanism, two different vascular anomalies may occur at the same region. We present a patient with VTN and NA combination which we think serves as an example for a rare twin spotting phenomenon in the literature.