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Catatonia in an adolescent with velo‐cardio‐facial syndrome
Author(s) -
Faedda Gianni L.,
Wachtel Lee E.,
Higgins Anne Marie,
Shprintzen Robert J.
Publication year - 2015
Publication title -
american journal of medical genetics part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.064
H-Index - 112
eISSN - 1552-4833
pISSN - 1552-4825
DOI - 10.1002/ajmg.a.37087
Subject(s) - catatonia , psychiatry , schizophrenia (object oriented programming) , psychosis , schizoaffective disorder , psychology , anxiety , autism spectrum disorder , bipolar disorder , social anxiety , autism , mood , clinical psychology , medicine
Velo‐cardio‐facial syndrome (VCFS) is the most common microdeletion syndrome in humans and is probably the most frequent genetic cause of psychosis currently known. Many psychiatric disorders have been reported to occur in people with VCFS including, but not limited to schizophrenia, unipolar and bipolar mood disorders (with or without psychotic features), schizoaffective disorder, psychosis NOS, social phobia, generalized and separation anxiety, obsessive‐compulsive disorder, autism spectrum disorder, cognitive impairment, and ADHD. This report describes the psychiatric onset and development of catatonia in an adolescent female with VCFS that was undiagnosed until 15 years of age. Catatonia may be a relatively common presentation in people with VCFS with treatment‐refractory psychiatric manifestations. © 2015 Wiley Periodicals, Inc.