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Grade II pilocytic astrocytoma in a 3‐month‐old patient with encephalocraniocutaneous lipomatosis (ECCL): Case report and literature review of low grade gliomas in ECCL
Author(s) -
Bieser Sarah,
Reis Martin,
Guzman Miguel,
Gauvain Karen,
Elbabaa Samer,
Braddock Stephen R.,
AbdelBaki Mohamed S.
Publication year - 2015
Publication title -
american journal of medical genetics part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.064
H-Index - 112
eISSN - 1552-4833
pISSN - 1552-4825
DOI - 10.1002/ajmg.a.37017
Subject(s) - pilocytic astrocytoma , etiology , medicine , lipomatosis , astrocytoma , glioma , pathology , pediatrics , cancer research
Encephalocraniocutaneous lipomatosis (ECCL) is a rare congenital syndrome with an unknown etiology. Since 1970, around 60 cases have been reported in English literature. ECCL is usually classified by cutaneous lesions and non‐progressive intracranial or spinal lipomas; however three cases of ECCL associated with low grade glioma (LGG) have been described. We report on the fourth case of LGG in a patient with ECCL; a grade II pilocytic astrocytoma with pilomyxoid features in a 3‐month‐old male, the youngest in literature. © 2015 Wiley Periodicals, Inc.