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Anthropometric measurements in Egyptian patients with osteogenesis imperfecta
Author(s) -
Aglan Mona S.,
Zaki Moushira E.,
Hosny Laila,
ElHoussini Rasha,
Oteify Ghada,
Temtamy Samia A.
Publication year - 2012
Publication title -
american journal of medical genetics part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.064
H-Index - 112
eISSN - 1552-4833
pISSN - 1552-4825
DOI - 10.1002/ajmg.a.35529
Subject(s) - arm span , anthropometry , medicine , osteogenesis imperfecta , circumference , body mass index , short stature , body height , sitting , body proportions , orthodontics , body weight , pediatrics , mathematics , anatomy , geometry , pathology
Osteogenesis imperfecta (OI) is a heritable skeletal disorder with bone fragility and often short stature. This study provides anthropometric measurements in Egyptian children with OI and determine variability among OI types classified according to Sillence et al. [Sillence et al. (1979); J Med Genet 16:101–116]. The study included 124 patients with OI. All were subjected to full clinical and radiological examination. Accordingly they were classified into types OI‐I (N = 16), OI‐III (N = 86), and OI‐IV (N = 22) following Sillence classification. Five anthropometric measurements were taken for each patient including: length or standing height, weight, head circumference, arm span, and sitting height. Three indices were calculated: body mass index, relative head circumference, and relative arm span. Results show that mean height standard deviation scores (SDS) was significantly reduced in OI type III and IV compared to type I. Mean sitting height SDS was significantly reduced in OI‐III than that of OI‐I. Mean relative head circumference was significantly increased in OI‐III than that in OI‐I and OI‐IV. Using anthropometry, this study was able to quantitatively assess the body physique in the different Sillence types of OI and the variability among them. © 2012 Wiley Periodicals, Inc.