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American Journal of Medical Genetics Part A: Volume 152A, Number 8, August 2010
Publication year - 2010
Publication title -
american journal of medical genetics part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.064
H-Index - 112
eISSN - 1552-4833
pISSN - 1552-4825
DOI - 10.1002/ajmg.a.33661
Subject(s) - smoothened , hedgehog , sonic hedgehog , cilium , patched , drosophila (subgenus) , biology , genetics , gene
The figure shows that when Sonic hedgehog binds to Patched 1, Smoothened shuttles from an endocytic vesicle to the cilium in vertebrates in contrast to Drosophila where it shuttles to the plasma membrane. See article by Cohen Jr. in this issue.