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Fragile X syndrome with anxiety disorder and exceptional verbal intelligence
Author(s) -
Angkustsiri Kathleen,
Wirojanan Juthamas,
Deprey Lesley J.,
Gane Louise W.,
Hagerman Randi J.
Publication year - 2008
Publication title -
american journal of medical genetics part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.064
H-Index - 112
eISSN - 1552-4833
pISSN - 1552-4825
DOI - 10.1002/ajmg.a.32118
Subject(s) - fragile x syndrome , anxiety , psychology , learning disability , depression (economics) , clinical psychology , intellectual disability , emotional intelligence , intelligence quotient , psychiatry , fragile x , developmental psychology , cognition , biochemistry , chemistry , economics , macroeconomics , gene
Fragile X syndrome (FXS) is often characterized by mental retardation. However, FXS is also associated with significant emotional and psychiatric problems, including anxiety, depression, attention difficulties, and learning disabilities in the presence of a normal IQ. This report describes a unique woman with the full mutation of FXS who has an exceptional profile of above‐average intelligence combined with significant impairments due to anxiety and learning disability. Women with FXS can present primarily with learning and emotional problems, and clinicians should consider FXS in these women regardless of their IQ. © 2008 Wiley‐Liss, Inc.